Sensitivity Analysis
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Revision as of 12:36, 16 May 2013 by BioUML wiki Bot (Talk | contribs)
- Analysis title
- File:Sensitivity-Analysis-icon.png Sensitivity Analysis
- Provider
- Institute of Systems Biology
- Plugin
- biouml.plugins.modelreduction (Model reduction plug-in)
Description
The method calculates sensitivities associated with the steady state of the purely temporal system
where c is the n-vector of species concentrations, α is the m-vector of systems parameters (which can include the initial conditions c0), and t (time) is the variable of integration.
The local sensitivities ∂c/∂αj are calculated via finite difference approximations
where css(αj) and css(αj+Δαj) correspond to the solutions of the algebraic systems f(c, αj) = 0 and f(c, αj+Δαj) = 0 respectively.
References
- H Rabitz, M Kramer, D Dacol, "Sensitivity analysis in chemical kinetics". Annu. Rev. of Phys. Chem., 34:419-461.
