Short term model of the heart output regulation

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Short-term heart output model

The model was developed by Y.V. Solodyannikov [1] and describes systemic blood flow through the certain reservoirs of the human body: the left ventricle, the arterial system and the venous system. The model has high time resolution with regime duration ~0.5 s. The ventricle is modeled as a pump switching between two regimes: systole and diastole. The model also operates with the oxygen debt concept and includes neuro-humoral regulation.

It was recreated using BioUML as a modular model. The recreated model contains:

  • 58 parameters,
  • 14 assignments,
  • 6 ordinary differential equations,
  • 2 descrete events corresponding to systole-diastole and diastole-systole transitions.

References

  1. Solodyannikov Y.V. The elements or mathematical modeling and hemodynamics system identification. Samara: The university of Samara, 1994.
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