Tools Comparison 2022

Here we collect information about similar software and their features in comparison with BioUML.
This comparison was made in February 2022. Previous was done in 2019 and is available at separate page Tools Comparison.

	BioUML	COPASI	iBioSim	CellDesigner	Tellurium	Morpheus
Capabilities
Model creation	visual\text-based	via tables	visual	visual	text-based	via tables
Simulation	+	+	+	via ext.tools	+	+
Parameter fitting	+	+	-	-	-	-
Model analysis	+	+	+	-	+	+
Database access	+	-	+	+	-	-
Formalism
ODE	+	+	+	+	+	+
Stochastic Gillespie-type	+	+	-	+	+	+
Algebraic	+	-	+	-	+	+
Discrete	+	+	+	+	+	+
Modular modeling	+	-	+	-	+	+
Combined formalisms	+	-	-	-	-	+
Agent-based	+	-	+	-	-	-
Rule-based	+	-	-	-	-	-
Population-based	+	-	-	-	-	-
Standards
SBML	l3v2, all tests passed	l3v1 except algebraic	l3v1	l3v1	l3v1	l3v1, partially
SBML comp	fully, all tests passed	-	partially	-	partially	partially
SBGN	+	export	-	+	-	-
SedML	+	-	-	-	+	-
Combine archive	+	+	+	+	+	+
SBOL	-	-	+	-	-	-
Antimony	+ (in standalone)	-	-	-	+	-
Bionetgen	+ (in standalone)	-	-	-	-	-
BioPAX	+	-	-	+	-	-
Availability
Windows	+	+	+	+	+	+
Linux	+	+	+	+	+	+
MacOS	+	+	+	+	+	+
Web application	+	-	-	-	-	-
Programming Language	Java	C++	Java	Java	Python	C++